Bruker announces three new orders for GHz NMR systems for functional structural biology and clinical phenomics research

UTRECHT, Netherlands–(BUSINESS WIRE)–At Euromar 2022, Bruker announced three new customer orders for GHz systems, which will incorporate new compact 1.0 GHz systems NMR magnets for structural biology applications and clinical research in single-tier laboratories. New Ascend Evo 1.0GHz The NMR magnet, operating at 4.2 Kelvin, allows functional structural biology and clinical phenomics researchers to delve into the structural details, linkage and dynamics of molecular structures and complexes for basic research in cell biology and pathobiology. It complements Bruker’s Advance Neo 1.1 GHz and 1.2 GHz NMR systems with two-stage 2 Kelvin magnets, which are typically used in shared national NMR facilities, such as the 1.2 GHz NMR at Dutch Ultra-High Field Magnetic Resonance Consortium, operating at the University of Utrecht.

A first new 1.0 GHz NMR order comes from the RIKEN Center for Biosystems Dynamics Research in Yokohama, Japan. The RIKEN team led by Dr. Ichio Shimada will use GHz NMR to study the dynamic structures of biomolecules in solution and to investigate the relationships between dynamic structures and biological function or pathobiology.

Bruker also confirms two 1.0 GHz NMR orders from major research centers and universities in Bilbao and Barcelona, ​​both in Spain, for clinical and biological research:

Professor Óscar Millet, Principal Investigator of the Precision Medicine and Metabolism Laboratory at CIC bioGUNE said: “The Ascend Evo 1.0GHz will advance our research in clinical metabolomics. This new magnet provides the highest resolution NMR to study molecular patterns and mechanism of action of prevalent and rare diseases in precision medicine, all in a one-story lab and with a small footprint.

Professor Miquel Pons Valles, group leader of the BioNMR group at the University of Barcelona and his team use biophysical methods, particularly NMR, as well as chemical biology, molecular biology, and computation to study proteins in regulatory processes, where dynamics are critical to functioning. The Ascend Evo 1.0 GHz will also advance their research on intrinsically disordered proteins (IDPs).

The recently introduced compact Ascend Evo 1.0GHz The NMR magnet has dramatically reduced space, weight and ceiling height requirements to fit most single-story labs. Along with a 65% reduction in helium consumption, this enables more structural biology principal investigators, universities and individual research centers, as well as advanced biopharmaceutical companies to access sensitivity and GHz NMR resolution to enable new research capabilities.

Another innovation is the new Bruker Heliosmart Recovery, a compact, easy-to-install system that collects helium evaporation from NMR magnets. Helium gas is stored in high pressure cylinders, which can be used by cryogen suppliers for reliquification. The Heliosmart Recovery can collect the steady state boiling of multiple NMR magnets in parallel with typical recovery rates of 80% to 85%.

Dr. Falko Busse, President of Bruker BioSpin Group, said: “We are delighted to announce the three new GHz controls, which will incorporate our innovative single-stage system Ascend Evo 1.0GHz magnet. This technological marvel brings the power of GHz NMR to more labs due to its small footprint, low maintenance requirements and low helium consumption.

Please join Bruker at Euromar at our stand to interact with our NMR and EPR teams.

About Bruker Corporation (Nasdaq: BRKR)

Bruker enables scientists to make groundbreaking discoveries and develop new applications that improve the quality of human life. Bruker’s high-performance scientific instruments and high-value analytical and diagnostic solutions enable scientists to explore life and materials at the molecular, cellular and microscopic levels. Working closely with our customers, Bruker enables innovation, improved productivity and customer success in life science molecular and cellular biology research, applied and pharmaceutical applications, microscopy and nanoanalysis, as well as in industrial applications. Bruker offers high-value, differentiated diagnostic and life science systems and solutions in the areas of preclinical imaging, clinical phenomics research, proteomics and multiomics, spatial and single-cell biology , structural functional biology and condensates, as well as clinical microbiology and molecular diagnostics. For more information, visit: www.bruker.com.

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