Biology – E JEMED http://e-jemed.org/ Fri, 11 Jun 2021 20:00:53 +0000 en-US hourly 1 https://wordpress.org/?v=5.7.2 https://e-jemed.org/wp-content/uploads/2021/05/default1-150x150.png Biology – E JEMED http://e-jemed.org/ 32 32 New discovery shows human cells can write RNA sequences into DNA https://e-jemed.org/new-discovery-shows-human-cells-can-write-rna-sequences-into-dna/ https://e-jemed.org/new-discovery-shows-human-cells-can-write-rna-sequences-into-dna/#respond Fri, 11 Jun 2021 18:02:43 +0000 https://e-jemed.org/new-discovery-shows-human-cells-can-write-rna-sequences-into-dna/ PHILADELPHIA – Cells contain machines that duplicate DNA into a new set that goes into a newly formed cell. This same class of machines, called polymerases, also creates RNA messages, which are like notes copied from the central repository of DNA recipes, so that they can be read more efficiently into proteins. But it was […]]]>


PHILADELPHIA – Cells contain machines that duplicate DNA into a new set that goes into a newly formed cell. This same class of machines, called polymerases, also creates RNA messages, which are like notes copied from the central repository of DNA recipes, so that they can be read more efficiently into proteins. But it was believed that polymerases only worked in one direction from DNA to DNA or RNA. This prevents RNA messages from being rewritten into the main genomic DNA cookbook. Now, researchers at Thomas Jefferson University are providing the first evidence that RNA segments can be rewritten into DNA, potentially challenging the central dogma of biology and could have broad implications affecting many fields. of biology.

“This work opens the door to many other studies that will help us understand the importance of having a mechanism to convert RNA messages to DNA in our own cells,” says Richard Pomerantz, PhD, associate professor of biochemistry and of Molecular Biology at Thomas Jefferson University. . “The reality that a human polymerase can do this with great efficiency raises many questions. For example, this finding suggests that RNA messages can be used as templates to repair or rewrite genomic DNA.

The work was published on June 11 in the journal Scientists progress.

With first author Gurushankar Chandramouly and other collaborators, Dr Pomerantz’s team began by studying a very unusual polymerase, called theta polymerase. Of the 14 DNA polymerases found in mammalian cells, only three do most of the work of duplicating the entire genome to prepare for cell division. The other 11 are mainly involved in the detection and repair of breaks or errors in DNA strands. Theta polymerase repairs DNA, but is very error prone and causes many errors or mutations. The researchers therefore noticed that some of the “bad” qualities of theta polymerase were those that it shared with another cellular machine, although one more common in viruses – reverse transcriptase. Like Pol theta, HIV reverse transcriptase acts like DNA polymerase, but can also bind to RNA and read RNA back into a strand of DNA.

In a sleek series of experiments, the researchers tested theta polymerase against HIV reverse transcriptase, which is one of the best-studied of its kind. They showed that theta polymerase was able to convert RNA messages to DNA, which it did as well as HIV reverse transcriptase, and actually did a better job than when duplicating DNA into DNA. Theta polymerase was more efficient and introduced fewer errors when using an RNA template to write new DNA messages than when duplicating DNA into DNA, suggesting that this function could be his main focus in the cell.

The group collaborated with the lab of Dr. Xiaojiang S. Chen at USC and used X-ray crystallography to define the structure and found that this molecule was able to change shape in order to adapt to the d molecule. Bigger RNA – a feat unique among polymerases.

“Our research suggests that the main function of theta polymerase is to act as a reverse transcriptase,” explains Dr. Pomerantz. “In healthy cells, the purpose of this molecule may be the repair of DNA by RNA. In unhealthy cells, such as cancer cells, theta polymerase is highly expressed and promotes cancer cell growth and Drug resistance. It will be exciting to better understand how RNA theta polymerase activity contributes to DNA repair and cancer cell proliferation. “

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This research was funded by NIH grants 1R01GM130889-01 and 1R01GM137124-01, and R01CA197506 and R01CA240392. This research was also funded in part by a grant from the Tower Cancer Research Foundation. The authors do not report any conflict of interest.

Article reference : Gurushankar Chandramouly, Jiemin Zhao, Shane McDevitt, Timur Rusanov, Trung Hoang, Nikita Borisonnik, Taylor Treddinick, Felicia Wednesday Lopezcolorado, Tatiana Kent, Labiba A. Siddique, Joseph Mallon, Jacklyn Huhn, Zainab Shoda, Ekaterina Kashjiang Starkand Xiaoji Chen and Richard T. Pomerantz, “Pol theta reverse transcribes RNA and promotes RNA-based DNA repair”, Science Advances, DOI: 10.1126 / sciadv.abf1771, 2021.

Media contact: Edyta Zielinska, 267-234-3553, edyta.zielinska@jefferson.edu

Warning: AAAS and EurekAlert! are not responsible for the accuracy of any press releases posted on EurekAlert! by contributing institutions or for the use of any information via the EurekAlert system.



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Accenture, Oracle, Cisco Systems – The Manomet Current https://e-jemed.org/accenture-oracle-cisco-systems-the-manomet-current/ https://e-jemed.org/accenture-oracle-cisco-systems-the-manomet-current/#respond Fri, 11 Jun 2021 06:03:27 +0000 https://e-jemed.org/accenture-oracle-cisco-systems-the-manomet-current/ MRI Precision Reports recently introduced a new title on “Global Cell Biology Cloud Computing Market: Industry Analysis, Size, Share, Growth, Trends and Forecast 2021-2027“From its database employing various methodologies, it aims to examine and present deep and accurate data regarding the global Cell Biology Cloud Computing market. The report provides the study with in-depth overview, […]]]>


MRI Precision Reports recently introduced a new title on “Global Cell Biology Cloud Computing Market: Industry Analysis, Size, Share, Growth, Trends and Forecast 2021-2027“From its database employing various methodologies, it aims to examine and present deep and accurate data regarding the global Cell Biology Cloud Computing market. The report provides the study with in-depth overview, outlining the scope of the product / industry and elaborates the outlook and market status (2021-2026).

  • Market Snapshot
  • Key players and competitive landscape
  • Growth drivers and constraints
  • Segmentation
  • Regional analysis

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Main competitive players:

Accenture, Oracle, Cisco Systems, Amazon Web Services, Technologie DXC, Benchling, IPERION, IBM, Dell Emc, ScaleMatrix, NovelBio

On the basis of product type, the report describes the share of major product types in the regional market. Products mentioned as follows: Public Cloud Computing, Private Cloud Computing, Hybrid Cloud Computing.

The report defines the major application share of the global market. Application mentioned as follows: Genomics, diagnostics, clinical trials, pharmaceutical manufacturing, others.

The Cell Biology Cloud Computing report through its overview section provides the overall scenario and global Cell Biology Cloud Computing market dynamics with its definition and other details. Furthermore, the Key Players and Competitive Landscape segment of the report involves various players who actively participate and compete in the global market. The report also concerns new entrants in the market. Major market players include. The report encompasses the major manufacturers along with their respective share in the global market in terms of revenue. Additionally, he mentions their tactical milestones over the past few years, leadership changes and investments in product innovation to help make informed decisions and also to stay ahead of the competition.

Moving on to the Growth Drivers and Constraints section, one will be presented with all the factors which are directly or indirectly contributing to the growth of the global Cell Biology Cloud Computing Market. To become familiar with market growth statistics, it is essential to assess the various market drivers. In addition, the report also puts forth existing trends as well as new and possible growth opportunities in the global market. Moreover, the report includes the factors which can possibly hamper the growth of the market. Understanding these factors is just as crucial as they help in understanding the weaknesses in the market.

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Global Cell Biology Cloud Computing market segmentation segregates the market on the basis of different aspects such as further each segment is elaborated by providing all essential details along with growth analysis for the forecast period . The report also divides the market by region into North America, Europe, Asia-Pacific, Middle East & Africa, and Latin America. The regional analysis covers the assessment of volume and income for each region as well as their respective countries. In addition, the report also comprises various aspects of the market such as import and export, supply chain value, market share, sales, volume, etc.

Primary and secondary approaches are used by analysts and researchers to compile this data. So, this Global Cell Biology Cloud Computing Market: Industry Analysis, Size, Share, Growth, Trends, and Forecasts 2021-2027 report aims to orient readers to better, more insightful, and clearer facts and data of the Global Cloud Biology. Computer market.

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Bay scallop recreational season kicks off as biologists strive to maintain population https://e-jemed.org/bay-scallop-recreational-season-kicks-off-as-biologists-strive-to-maintain-population/ https://e-jemed.org/bay-scallop-recreational-season-kicks-off-as-biologists-strive-to-maintain-population/#respond Thu, 10 Jun 2021 15:41:07 +0000 https://e-jemed.org/bay-scallop-recreational-season-kicks-off-as-biologists-strive-to-maintain-population/ State biologists have worked to bring back bay scallop populations by doing everything from population monitoring to a Scallop Sitter program. The efforts have worked well enough to allow selective recreational scallop fishing in parts of the state. The decline in bay scallop populations in recent decades means that activity is closely monitored by the […]]]>


State biologists have worked to bring back bay scallop populations by doing everything from population monitoring to a Scallop Sitter program. The efforts have worked well enough to allow selective recreational scallop fishing in parts of the state.

The decline in bay scallop populations in recent decades means that activity is closely monitored by the Florida Fish and Wildlife Conservation Commission (FWC). Recreational bay fishing is only permitted between the Hernando and Pasco County line north of Mexico Beach. Each region has its own dates.

The Fenholloway River across the Suwannee River opens June 15 and will remain open until Labor Day. This includes state waters in Dixie County, parts of Taylor County, and the towns of Keaton Beach and Steinhatchee, which are among the state’s primary scallop fishing grounds. The coastal area has rivers that flow into the gulf stirring the right mixture of fresh and salt water.

Bay scallops are mollusks and have shells. They live in seagrass beds and are known for their fascinating divers with a row of blue eyes sticking out of their shells. The eyes alert the scallop to changes in light, but are also eye-opening for scallop hunters, as they quickly draw attention to a scallop’s location in sea grass. Hunters can be pinched by the scallop which closes its two shells. Sometimes scallop hunters use dip nets to catch invertebrates.

But hunting isn’t the only way to engage with Florida Bay scallops. FWC biologists work with the public to closely monitor and restore their populations.

Declining water quality, among other environmental factors, has led to a decline in Florida Bay scallop populations, which were once abundant from West Palm Beach on the Atlantic coast to Pensacola in the enclave. Florida Bay scallops in recent years have been found in isolated populations scattered along the west coast. The majority are found in coastal seagrass beds from Tarpon Springs in Pinellas County to Port St. Joe in Gulf County, according to the FWC.

Scallops are sensitive to changing environmental conditions, such as loss of seagrass, increased freshwater, and the release of sediment. Since Florida Bay scallops typically only live for a year, local populations are more susceptible to periodic collapses.

The Florida Fish and Wildlife Research Institute (FWRI) used a Scallop keeper program to compensate for population losses in certain regions. The program, funded by restoration money set aside after the Deepwater Horizon oil spill, involves collecting juvenile scallops and placing them in cages of fifty in some underpopulated areas. FWRI is asking certain eligible community members to monitor young scallops. By placing scallops in cages, they are protected from predators and humans.

To collect juvenile scallops for the Scallop Sitter program, FWRI is organizing a Scallop rodeo. Residents of certain areas are asked to collect buckets of 200 live scallops and turn them into biologists to redistribute in the cages.

The Scallop Sitter program is only one part of a 10-year restoration plan put in place by FWRI in 2016. The effort also includes the release of hatchery-raised bay scallops into the wild, redistribution of scallops from naturally harvested berry and bay scallop population counts.

The daily bag limit for the Fenholloway River during the Suwannee River season is one gallon of whole scallops in the shell or one cup of shelled scallops per person with a maximum of five gallons of whole scallop meat or four cups per vessel. Regular season limits are two gallons of whole bay scallops in the shell or 1 quart of bay scallop meat per person, with a maximum of 10 gallons of whole bay scallops in the shell or 1/2 gallon ( four pints) of peeled bay scallop meat per vessel. Throughout the season and throughout the region, vessel limits do not allow an individual to exceed their personal baggage limit.

Additional dates for the bay scallop season are as follows:

scallop seasons with map for 2021

Baie St. Joseph / Gulf County: From August 16 to September 24. The region includes all state waters from the Mexico Beach Canal in Bay County to the westernmost point of St. Vincent Island in Franklin County.

Franklin County to northwest Taylor County (including Carrabelle, Lanark and St. Marks): from July 1 to September 24. The region includes all state waters from the westernmost point of St. Vincent Island in Franklin County to the mouth of the Fenholloway River in Taylor County.

Levy, Citrus and Hernando counties (including Cedar Key, Crystal River and Homosassa): from July 1 to September 24. The region includes all state waters from the mouth of the Suwannee River in Levy County to the Hernando – Pasco County line.

Pasco County: Open 10 days from the third Friday in July (July 16-25, 2021). The region includes all state waters south of the Hernando – Pasco County line and north of Anclote Key Lighthouse, including all of the waters of the Anclote River.


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microscopic frozen animals brought back to life after 24,000 years | Biology https://e-jemed.org/microscopic-frozen-animals-brought-back-to-life-after-24000-years-biology/ https://e-jemed.org/microscopic-frozen-animals-brought-back-to-life-after-24000-years-biology/#respond Wed, 09 Jun 2021 19:25:37 +0000 https://e-jemed.org/microscopic-frozen-animals-brought-back-to-life-after-24000-years-biology/ Microscopic multicellular animals called bdelloid rotifers are known for their ability to survive extremely low temperatures. They would have survived 6 to 10 years when frozen between minus 20 and 0 degrees Celsius. Today, an international team of biologists has successfully revived bdelloid rotifers frozen in Siberian permafrost for 24,000 years. A bdelloid rotifer. Image […]]]>


Microscopic multicellular animals called bdelloid rotifers are known for their ability to survive extremely low temperatures. They would have survived 6 to 10 years when frozen between minus 20 and 0 degrees Celsius. Today, an international team of biologists has successfully revived bdelloid rotifers frozen in Siberian permafrost for 24,000 years.

A bdelloid rotifer. Image credit: Michael Plewka.

In permanently frozen natural habitats, some organisms can be preserved for hundreds to tens of thousands of years.

For example, stalks of Antarctic moss have successfully regrown from a sample over a millennium old covered in ice for about 400 years.

Likewise, whole campion plants were regenerated from seed tissues preserved in a 32,000-year-old relict permafrost, and nematodes were resuscitated from the permafrost of two localities in northeastern Siberia, with sediment sources dating back more than 30,000 years.

“Our report is the strongest evidence to date that multicellular animals called bdelloid rotifers could withstand tens of thousands of years in cryptobiosis, the almost completely stopped metabolic state,” said researcher Dr. Stas Malavin. at the Institute of Physico-Chemistry and Biology. Problems in soil science.

Dr Malavin and his colleagues used radiocarbon dating to determine that the rotifers they recovered from Siberian permafrost were around 24,000 years old.

The microscopic animals belonged to the genus Adineta, and aligned with contemporary species Adineta vaga collected in Belgium.

Once thawed, the rotifers were able to reproduce in a clonal process called parthenogenesis.

To track the process of freezing and retrieving ancient creatures, researchers frozen and then thawed dozens of rotifers in the lab.

Studies have shown that rotifers can resist the formation of ice crystals that occurs during slow freezing.

This suggests that they have a mechanism to protect their cells and organs from damage at extremely low temperatures.

“The bottom line is that a multicellular organism can be frozen and stored as such for thousands of years and then come back to life – a dream of many writers of fiction,” said Dr Malavin.

“Of course, the more complex the organism, the more difficult it is to keep it alive frozen and, for mammals, this is not currently possible.”

“Yet to go from a single-celled organism to an organism with a gut and a brain, although microscopic, is a big step forward.”

“It’s not yet clear what it takes to survive on the ice for even a few years and if jumping to the thousands makes a big difference. This is a question that requires further study.

The team’s article appeared in the June 7, 2021 issue of the journal Current biology.

_____

Lyubov Shmakova et al. 2021. A living bdelloid rotifer from a 24,000-year-old arctic permafrost. Current biology 31 (11): R712-R713; doi: 10.1016 / j.cub.2021.04.077



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Biden to cut Pentagon money for pandemic prevention https://e-jemed.org/biden-to-cut-pentagon-money-for-pandemic-prevention/ https://e-jemed.org/biden-to-cut-pentagon-money-for-pandemic-prevention/#respond Tue, 08 Jun 2021 22:41:15 +0000 https://e-jemed.org/biden-to-cut-pentagon-money-for-pandemic-prevention/ President Joe Biden has proposed slashing the Pentagon’s budget by nearly half for the main US government program of preventing, detecting and responding to global epidemics, a move to which even the staunchest allies of the White House on Capitol Hill clash as the nation continues to fight the covid19 pandemic. The so-called Biological Threat […]]]>


President Joe Biden has proposed slashing the Pentagon’s budget by nearly half for the main US government program of preventing, detecting and responding to global epidemics, a move to which even the staunchest allies of the White House on Capitol Hill clash as the nation continues to fight the covid19 pandemic.

The so-called Biological Threat Reduction Program detects and combats emerging global diseases that can threaten US troops and, ultimately, the world’s population. In fact, the Pentagon program funded a lab in Thailand that in January 2020 detected the first case of the novel coronavirus outside of China.

The Defense Department wants the program’s budget for fiscal year 2022 to be set at $ 124 million, 45% below the current level, according to the Pentagon’s budget justification documents, which were released earlier. this month.

The budget documents provide incomplete explanations at best for the proposed reduction, which has not been reported previously. Administration officials have yet to respond to several requests for a fuller explanation of the proposed reduction.

“Deeply disturbing”

The proposed funding cut comes as U.S. intelligence agencies and scientists predict pandemics will become more common and COVID-19 still rages in many countries and persists in America.



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Molecular Biology Enzymes and Kits and Reagents Market Size and Growth 2021-2028 | Main suppliers – Thermo Fisher Scientific, Merck KGaA, Promega Corporation, New England Biolabs, Illumina, Takara Bio, Qiagen NV, Agilent Technologies – KSU https://e-jemed.org/molecular-biology-enzymes-and-kits-and-reagents-market-size-and-growth-2021-2028-main-suppliers-thermo-fisher-scientific-merck-kgaa-promega-corporation-new-england-biolabs-illumina-takara-bi/ https://e-jemed.org/molecular-biology-enzymes-and-kits-and-reagents-market-size-and-growth-2021-2028-main-suppliers-thermo-fisher-scientific-merck-kgaa-promega-corporation-new-england-biolabs-illumina-takara-bi/#respond Mon, 07 Jun 2021 04:53:34 +0000 https://e-jemed.org/molecular-biology-enzymes-and-kits-and-reagents-market-size-and-growth-2021-2028-main-suppliers-thermo-fisher-scientific-merck-kgaa-promega-corporation-new-england-biolabs-illumina-takara-bi/ Sample download request Request a discount Company Profile New Jersey, United States, – This detailed market research captures the growth potential of the Molecular Biology Enzymes and Kits and Reagents Market and can help stakeholders understand the most important trends and prospects for the Molecular Biology Enzymes and Kits and Reagents market and to identify […]]]>


New Jersey, United States, – This detailed market research captures the growth potential of the Molecular Biology Enzymes and Kits and Reagents Market and can help stakeholders understand the most important trends and prospects for the Molecular Biology Enzymes and Kits and Reagents market and to identify growth opportunities and competitive scenarios. The report also focuses on data from other primary and secondary sources and is analyzed using various tools. This will help investors better understand the growth potential of the market and determine the size and opportunities for investors. This analysis also provides detailed information for each segment of the global Molecular Biology Enzymes, Kits, and Reagents market.

The report was cited as the most recent event in the market related to the COVID-19 outbreak. This epidemic has brought about dynamic changes in the industry and in the macroeconomic scenario. This report analyzes the impact of the COVID-19 pandemic on market growth and sales. The report also includes an in-depth analysis of the current and future impact of the pandemic and an analysis of post-COVID-19 scenarios.

The report covers the following key players in the Molecular Biology Enzymes and Kits and Reagents market:

• Thermo Fisher Scientific
• Merck KGaA
• Promega Corporation
• New England Biolabs
• Illumina
• Takara Bio
• Qiagen SA
• Agilent Technologies
• F. Hoffmann-La Roche SA
• Bio Basic Inc.
• Jena Bioscience GmbH
• Molecular biology resources

Molecular Biology Enzymes and Kits and Reagents Market: Key Enablers

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Report attribute Details
Market size available for years 2021 – 2028
Reference year considered 2021
Historical data 2015 – 2019
Forecast period 2021 – 2028
Quantitative units Revenue in millions of USD and CAGR from 2021 to 2028
Covered segments Types, applications, end users, etc.
Cover of the report Revenue forecast, company ranking, competitive landscape, growth factors and trends
Regional scope North America, Europe, Asia-Pacific, Latin America, Middle East and Africa
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Due to regional segmentation, the market is divided into major regions North America, Europe, Asia-Pacific, Latin America, Middle East and Africa. Further, the regional analysis covers the market split and major players by country.

The research report offered by Verified Market Reports provides an updated view of the global Molecular Biology Enzymes and Kits and Reagents Market. The report provides a detailed analysis of key trends and emerging market factors that might affect the growth of the industry. Additionally, the report studies the market characteristics, competitive landscape, market size and growth, regional breakdown, and strategies for this market.

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Providence-Biological E Covid-19 vaccine to undergo phase two trials this month https://e-jemed.org/providence-biological-e-covid-19-vaccine-to-undergo-phase-two-trials-this-month/ https://e-jemed.org/providence-biological-e-covid-19-vaccine-to-undergo-phase-two-trials-this-month/#respond Sun, 06 Jun 2021 06:23:28 +0000 https://e-jemed.org/providence-biological-e-covid-19-vaccine-to-undergo-phase-two-trials-this-month/ A Canadian vaccine developer who announced a partnership with an Indian company last week hopes to begin phase two trials of its Covid-19 vaccine this month. Providence Therapeutics, headquartered in Calgary, Alta., Is confident it will be able to send a shipment of the PTX-COVID19-B vaccine candidate to its Indian partner, Biological E, based in […]]]>


A Canadian vaccine developer who announced a partnership with an Indian company last week hopes to begin phase two trials of its Covid-19 vaccine this month.

Providence Therapeutics, headquartered in Calgary, Alta., Is confident it will be able to send a shipment of the PTX-COVID19-B vaccine candidate to its Indian partner, Biological E, based in Hyderabad, in July so that trials can begin in India, too, before emergency use authorization is requested from health authorities.

Brad Sorenson, CEO of Providence, told HT the company expects to submit additional data requested by Health Canada soon.

“As soon as we get it, which could be as early as next week, but I expect it will be in two weeks, we will submit it to Health Canada and proceed with our phase two trials,” said Sorenson.

Sorenson was hoping that the first shipment of vaccine, if approved, will begin arriving in India from Providence’s manufacturing facility in the province of Manitoba by the end of this year.

“If all goes well, we should have the approval before the end of the year and we should have doses to start distributing immediately once the approval is received,” he said.

Providence will manufacture a batch of 30 million doses, with Biological E manufacturing between 600 million and one billion doses thereafter.

Half of this capacity made in India will be kept by Biological E and the other half donated to Providence for sale abroad.

Sorenson said Providence is exploring partnerships to manufacture the vaccine so that the high demand for a vaccine against the coronavirus can be met. “The nature of this agreement is to make very low cost messenger RNA vaccines,” he said.

Providence is also in talks with the World Health Organization (WHO) to participate in the United Nations body’s “solidarity trials”, which it describes as “one of the largest international randomized trials for treatments. of Covid-19, enrolling nearly 12,000 patients in 500 hospital sites in more than 30 countries ”.

While acceptance is not guaranteed, Sorenson said he was convinced Providence had “a world-class vaccine” and that the WHO was “very happy to have an mRNA vaccine of this caliber participating in it. ‘solidarity test’.

The WHO clearance will also open up use of the vaccine globally, and Sorenson hoped it would be part of the global Covax vaccine distribution facility.

Interestingly, Providence is working on another version of the vaccine, PTX-COVID19-LT, which is in the investigation phase.

Sorenson said that “the immunity that would be generated would last longer,” so a booster dose would not necessarily be needed every year.

“You might be able to get this picture and it might be good for five or ten years, so it would be very effective for the whole world; and especially for low and middle income countries where the deployment of vaccines on an annual basis is very prohibitive. “



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Strategic Risk Board Experts Respond to Biden Budget on Climate, Biological, and Nuclear Threats – Homeland Security Today https://e-jemed.org/strategic-risk-board-experts-respond-to-biden-budget-on-climate-biological-and-nuclear-threats-homeland-security-today/ https://e-jemed.org/strategic-risk-board-experts-respond-to-biden-budget-on-climate-biological-and-nuclear-threats-homeland-security-today/#respond Sat, 05 Jun 2021 09:51:11 +0000 https://e-jemed.org/strategic-risk-board-experts-respond-to-biden-budget-on-climate-biological-and-nuclear-threats-homeland-security-today/ Perhaps more than any executive budget submission in history, the first budget published by the Biden administration takes the seriousness of transnational systemic security risks seriously and begins significant investments to address them. Yet there will still be work to be done after the FY2022 budget to ensure that the federal government’s resources are commensurate […]]]>


Perhaps more than any executive budget submission in history, the first budget published by the Biden administration takes the seriousness of transnational systemic security risks seriously and begins significant investments to address them. Yet there will still be work to be done after the FY2022 budget to ensure that the federal government’s resources are commensurate with these threats. Here are the first reactions to the budget of several experts from the Strategic Risk Board (CSR) on these issues.

On climate security

“One thing is clear about the climate investments in this budget request – they are actually investments in mission capacity. Investing in climate resilience means that you want to continue fulfilling your core mission, even when climate impacts worsen. Investing in more efficient systems means you are buying better performing systems. Far from any mandate that distracts from traditional combat capabilities, these investments all increase DoD’s ability to meet mission and readiness requirements in the face of emerging and growing environmental threats. – John Conger, Director, Center for Climate and Security

“The United States cannot tackle the climate crisis alone. I am therefore delighted to see that the budget proposes an increase in contributions to the Green Climate Fund, to help the countries most affected by the climate crisis to adapt. However, there is still a gap between what the United States promised under President Obama and what we are offering, so more needs to be done. Climate change is already contributing to severe instability and conflict risks in countries around the world, threatening US interests. How can we convince other countries to take bold action to reduce emissions and prevent catastrophic future security risks when we fail to help them deal with the security risks we have already bought? – Erin Sikorsky, Deputy Director of the Center for Climate and Security; Director, International Military Council on Climate and Security

“The Indo-Pacific is emerging as a key site of geopolitical contestation and climate vulnerability. The Biden administration may consider committing additional resources to strengthen the resilience of nations in the region, particularly in the area of ​​climate-smart infrastructure, both physical and human, and support for the resolution of related disputes. to transboundary waters. Such support should prioritize allies and partners, but other nations could also be included, to strengthen the momentum for cooperation in a region vital to the US national interest. – Sarang Shidore, Principal Investigator, Strategic Risk Board

“This budget (finally) launches the process of responding to the climate crisis in a manner commensurate with the threat. But the scale of investments in adaptation – and mitigation – must increase if we are to prevent a potentially unmanageable security landscape. We don’t have a lot of time, so now is the time to take it further. – Francesco Femia, co-founder and research director, The Council on Strategic Risks / The Center for Climate and Security

On biological threats

“The President has made it clear that tackling biological threats is a high priority. We have all seen the devastation they can cause. While there are positive increases in pandemic prevention in some areas, it is disappointing not to see this matched in the proposed defense budget. In particular, the President’s budget appears to curtail the Chemical and Biological Defense Program – which has made significant contributions to the COVID-19 response and harbors unique capabilities to respond to infectious disease threats – and the Cooperative Disease Reduction Program. Nunn-Lugar threats, which includes working with international partners on biological threat reduction. In the years to come, defense leaders will need to address this and increase those investments that are so essential to the United States’ strength, competitiveness, and international partnerships. “- Christine Parthemore, CEO, Strategic Risk Council

“Advanced technology for early warning systems and the rapid development of medical countermeasures are only effective with the proper infrastructure and a workforce trained to use it. We’ve already seen the Biden administration’s commitment to public health in this direction – more recently the administration announced $ 7.4 billion to support the training and hiring of public health workers for the next public health crisis. Ideally, the administration should commit similar resources to create a skilled workforce that will work on the research, development, testing and deployment of these technologies. In addition, the administration should devote additional resources to studying the national security, ethical and societal implications of these technologies as they emerge, made up of a diverse community of technologists, community leaders, specialists. social scientists, ethicists and other public and private stakeholders. Diverse and thoughtful contributions and discussions are the key to navigating the promises and dangers of emerging technologies ”- Dr Yong-Bee Lim, Fellow, Janne E. Nolan Center on Strategic Weapons, CSR

“The increased presence and role of the Department of Energy (DOE) and national laboratories underscore the administration’s vision that science and technology are integral to building a healthier, safer and more secure world. safer. The DOE’s national laboratories have historically been underutilized despite their immense capabilities as a repository of leading talent in science and technology, state-of-the-art facilities, and a melting pot for innovation in public partnerships. private. The proposed budgets indicate that these spaces should be harnessed to tackle everything from climate change to future pandemics, which is a welcome change from past trends. “- Dr Yong-Bee Lim, Fellow, Janne E. Nolan Center on Strategic Weapons, CSR

On nuclear threats

“As expected, given that the first review of the Biden administration’s nuclear posture is forthcoming, the nuclear weapons program in the President’s first budget request is mostly in continuity with Trump’s latest budget. But almost doubling Trump’s budget for the Long-Range Nuclear Cruise Missile (LRSO) – a destabilizing nuclear weapon that we don’t need for the bomber branch of the Triad – doesn’t make sense. -Andy Weber, Senior CSR Researcher and Former Deputy Secretary of Defense for Nuclear, Chemical and Biological Defense Programs

“Although the budget is aimed at modernizing the US nuclear arsenal, there is an expected gap to address the intersections between climate, nuclear and security. As the administration’s defense priorities indicate, nuclear issues are closely linked to geopolitical tensions (especially vis-à-vis China and Russia) – climate impacts are virtually guaranteed to intersect with these developments. . – Andrea Rezzonico, Deputy CEO & Deputy Director of the Converging Risks Lab, CSR

DOD’s FY22 application overview explicitly mentions how climate change will impact the Arctic region – and pave the way for greater opportunities for conflict. He could and should actively declare that this region is also surrounded by states with nuclear weapons and nuclear-powered infrastructure, including icebreakers. The Authority should incorporate this link into its strategic plans for the future. “- Andrea Rezzonico, Deputy CEO & Deputy Director of the Converging Risks Lab, CSR

This article first appeared at the Center for Climate and Security

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Adapting laboratory techniques to distance education https://e-jemed.org/adapting-laboratory-techniques-to-distance-education/ https://e-jemed.org/adapting-laboratory-techniques-to-distance-education/#respond Fri, 04 Jun 2021 17:42:11 +0000 https://e-jemed.org/adapting-laboratory-techniques-to-distance-education/ PICTURE: Pablo Perez-Pinera, left, and Karin Jensen developed remote lab exercises to help students learn common lab techniques. view After Credit: Karin Jensen The COVID-19 pandemic has forced instructors to adapt their courses for online learning. Classes in the laboratory were particularly difficult due to the lack of access to specialized equipment for distance learners. […]]]>


PICTURE: Pablo Perez-Pinera, left, and Karin Jensen developed remote lab exercises to help students learn common lab techniques. view After

Credit: Karin Jensen

The COVID-19 pandemic has forced instructors to adapt their courses for online learning. Classes in the laboratory were particularly difficult due to the lack of access to specialized equipment for distance learners. To overcome this challenge, researchers at the University of Illinois Urbana-Champaign designed a lab exercise to teach students how to use micropipettes, through distance learning, using home kits.

Micropipettes are common and essential laboratory instruments and are used in several fields including molecular biology, microbiology and biochemistry. They are used to accurately transfer very small volumes of liquid. To teach students how to use these instruments, researchers developed kits, costing $ 135 per student, which is a fraction of the cost of instructional equipment normally used for in-person lessons.

“Although laboratory kits have been developed previously, they did not focus on micropipetting skills,” said Karin Jensen, assistant professor of bioengineering, who worked with the associate professor of bio- engineering Pablo Perez-Pinera (ACPP) to develop the project. “In an effort to provide remote students with a lab experience, we have developed and shipped student kits. These kits contained materials and reagents allowing them to practice their technique and perform experiments from a distance.

Each kit contained a mini-scale, a glucometer, a pipet-aid and a set of micropipettes. Each student received the kit, an instructional video, and a lab manual. They were asked to follow the protocol step by step in order to learn how to dilute the glucose solutions correctly and to check their accuracy using the glucometer. They also shared their data with the instructors for comments and scoring.

Students also completed surveys and feedback forms on the effectiveness of these online courses. “We found that most of the students were excited to use lab equipment despite being in an online section,” Jensen said.

Researchers are now working to improve exercise. “Beyond COVID-19, there is still a need to develop distance lab learning opportunities for students who cannot attend labs in person,” Jensen said. “Remote lab activities, similar to what we describe, will be important in increasing access to STEM education.”

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The article “Remote lab exercise to develop micropipetting skills” was published in the Journal of Microbiology and Biology Education. The study was funded by the Department of Bioengineering and the Grainger College of Engineering at the University of Illinois at Urbana-Champaign.

Warning: AAAS and EurekAlert! are not responsible for the accuracy of any press releases posted on EurekAlert! by contributing institutions or for the use of any information via the EurekAlert system.



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Venezuelan biologist researches the microbiome https://e-jemed.org/venezuelan-biologist-researches-the-microbiome/ https://e-jemed.org/venezuelan-biologist-researches-the-microbiome/#respond Fri, 04 Jun 2021 04:46:45 +0000 https://e-jemed.org/venezuelan-biologist-researches-the-microbiome/ Antimicrobial practices the Venezuelan microbiologist recalled the results of his research. The mouth contains a large number of bacteria, many of which are not harmful and are even beneficial. However, others can cause infections. “It’s fascinating,” she said. “You can see the urbanization gradient very clearly”: as city dwellers we embrace the industrialized way of […]]]>


Antimicrobial practices

the Venezuelan microbiologist recalled the results of his research. The mouth contains a large number of bacteria, many of which are not harmful and are even beneficial. However, others can cause infections. “It’s fascinating,” she said. “You can see the urbanization gradient very clearly”: as city dwellers we embrace the industrialized way of life and live in cities; on the other hand, they adopt “many practices” which are antimicrobial.

And it is not only about hygiene habits, but also about the consumption of antibiotics, the use of antibacterial substances and preservatives. “Tin cans don’t rot just because they’re full of microbial inhibitors; in this culture of processed and preserved foods, there are a lot of antimicrobial agents that we also consume ”.

The harmful effects of ultra-processed foods on health, according to new studies

“All these modern practices seem to cause a loss of diversity (of the microbiota) and with that functions are lost. At the same time, an increase in immune defenses and metabolic diseases is associated with modern and urban lifestyles, and we believe these 2 things are causally related. We lose important functions of the microbiota and, if this impact occurs very early in life, it leads to poor development of the immune system and the metabolic system, ”she explains.

She also cautions that determining causation in humans is very complicated and that doing clinical trials with people is very expensive. So the first step was to experiment with mice.

Cleaning habits

The biologist expert points out that in remote communities, which are very small villages, there are no farming or animal production systems. And that has a direct effect on them.

“The jungle villages have their own parasites, but unless they are introduced through contact with strangers, they do not have our common infectious pathogens, the agriculture-related bacteria (virulent Escherichia coli, Salmonella ) or zoonotic viruses (influenza, HIV) ”, She wrote in her scientific article of 2016. And this observation was recalled during our conversation:“ You realize that many of our gastrointestinal pathogens, most of them, come from our meat and poultry production systems, ”she adds.

The experience of living with Aboriginal communities also allowed her to learn about the cleaning habits of some of them. “They bathe several times a day in the river; their children spend a lot of time in the river. They don’t use soap, but to be clean you realize that you don’t really need to use soap ”.

“I stopped showering and life went on,” says the preventive medicine expert and Yale professor who also wonders how and how much we bathe. Typically, when we arrive, the first few days, we use iodine: 1 drop per liter of water ”.

“On day 4, we don’t know where we left him. Instead of going to the river, which is far away, we end up consuming the water that they stored before. You know, all the children in the community play with this water; they even put their hands in it and sometimes their hands have feces, but no one has pathogens to pass on, in part because there is no E. cow coli or Salmonella; there are also no pathogens of zoonotic origin and, inexorably, we all end up drinking this water ”. “If we are going to stay there for 3 weeks, we are not going to fetch water from the river so often but nobody gets sick. It was an excellent teaching, ”she comments.

Their eating habits

In some of the communities visited by Domínguez, “any mother dresses with her baby and goes to work. She wears it first on her chest and then behind her. These women do a terrific exercise with a weight on them and they have the correct postures. They squat down, which is a very healthy position ”.

Families “don’t sit down to eat 3 times a day like we do. They usually sit together at night and eat together to talk. During the day there is a permanent eating habit. They eat a serving of cassava, then a banana, then another fruit, and they continue to do so all day. They also have pineapples to die for, ”she said with a small smile. “If you continue to eat portions of fruit and cassava all day, then you go through this day without feeling hungry.”

Aerial photos show that the Yanomami tribe in the Amazon remains isolated from the outside world. “Then in the evening, there is a fish soup with tubers or, if there was hunting, red meat. But what they eat red meat is like a meatball, literally every week. That’s the portion and hopefully twice a week ”.

“They go hunting and, on their return, they bite the prey and what they touch in person, because they share it with the community, it is a meatball. It’s a super healthy diet. It is not a vegetarian diet, although it is truly exceptional to eat red meat. They eat fish soup every day. The pot is constantly boiling; they pour water on it, take out the fish, eat it, put in another fish, and this same process is repeated over and over again. It’s very interesting how you don’t need to use soaps or detergents ”.

Results of a social experiment

“We did an experiment and we studied ourselves, all 7 visitors. We stopped using shampoo, soap, toothpaste, but we did not give up using our toothbrushes. After that, we told them, “You can optimize health, we made a lot of mistakes. You have to understand why your diet and physical activity are appropriate, ”explains Domínguez.

“We said to ourselves: how far are we ready to give up, especially substances, chemicals? A couple of scientists, she comments, even stopped wearing their boots and went barefoot to this village. “Soon after, they ended up removing the chiggers (very small organisms) from their feet. Besides, I didn’t eat any worms, “she says. But some of her colleagues did.

“We wanted to study the following thing: If you fully incorporated into their diet and stopped using shampoos, detergents, soaps and toothpastes… How much does your microbiota change?

“We did not discuss the microbiota of all the inhabitants, but there were a couple of children, respectively 4 and 6 years old, who were the children of 2 doctors and who increased their diversity and grew closer. It was a very small study, a pilot study, but it opened up the possibility of asking: how long does the development of the human microbiota take?

And that’s what we believe; that during our first years of life, the composition of the gut microbiome is assembled and will persist into adulthood, when this microbial ecosystem reaches a state of equilibrium.

Another research study, in which Domínguez is a co-author, analyzed the microbiota of a group of individuals and found that after 3 years, children could no longer be distinguished from adults in terms of microbiota.

To be continued……

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