Evolutionary Modeling – E JEMED http://e-jemed.org/ Wed, 22 Jun 2022 19:01:18 +0000 en-US hourly 1 https://wordpress.org/?v=5.9.3 https://e-jemed.org/wp-content/uploads/2021/05/default1-150x150.png Evolutionary Modeling – E JEMED http://e-jemed.org/ 32 32 Amazon AI Researchers Open-Source ‘Syne Tune’: A New Python Library for Distributed HPO Focuses on Enabling Machine Learning Reproducible Search https://e-jemed.org/amazon-ai-researchers-open-source-syne-tune-a-new-python-library-for-distributed-hpo-focuses-on-enabling-machine-learning-reproducible-search/ Wed, 22 Jun 2022 17:18:52 +0000 https://e-jemed.org/amazon-ai-researchers-open-source-syne-tune-a-new-python-library-for-distributed-hpo-focuses-on-enabling-machine-learning-reproducible-search/ Deep learning models with billions of parameters are trained via stochastic gradient-based optimization, thanks to powerful algorithms, systems and hardware advancements. These algorithms include several hyperparameters that are essential for efficient performance. Hyperparameter tuning is needed to control the behavior of a machine learning model. If our hyperparameters are not set correctly, our anticipated model […]]]>

Deep learning models with billions of parameters are trained via stochastic gradient-based optimization, thanks to powerful algorithms, systems and hardware advancements. These algorithms include several hyperparameters that are essential for efficient performance. Hyperparameter tuning is needed to control the behavior of a machine learning model. If our hyperparameters are not set correctly, our anticipated model parameters will not minimize the loss function, leading to poor results. The poor result suggests that our model has other flaws. In reality, the accuracy or confusion matrix will be worse.

Many hyperparameters exist such as the learning rate, the type of regularization, the degree and the size of the layers of the neural network. Automating the tuning of these hyperparameters and accelerating the training of neural network weights is necessary if domain experts and industry practitioners benefit from the latest deep learning technologies. Even for specialists, settling them requires a lot of time and effort; choosing the best hyperparameter configuration often depends on factors such as cost or latency.

To solve this problem, AWS researchers introduced Syne Tune, a library for large-scale distributed hyperparameter optimization (HPO). Syne Tune’s modular design makes it easy to add new optimization algorithms and switch between different runtime backends to support experimentation. For large-scale evaluations of distributed asynchronous HPO algorithms on tabulated and surrogate benchmarks, Syne Tune offers an efficient simulator backend and benchmarking package that promotes repeatable benchmarking. On well-known benchmarks from the literature, we demonstrate these features using a variety of advanced gradientless optimizers, including multi-fidelity and transfer learning techniques.

Two use cases illustrate the benefits of Syne Tune for restricted and multi-purpose HPO applications: the first considers hyperparameters that lead to suitable solutions. At the same time, the second automatically selects machine types in addition to common hyperparameters.

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Here are the main features of Syne Tune:

• Broad Baseline Coverage: Syne Tune implements various HPO techniques, including evolutionary search, Bayesian optimization, and random search, eliminating implementation bias from comparisons.

• Backend-neutral: Syne Tune makes it easy to modify the runtime backend. New backends can be incorporated as they come with a generic API.

• Advanced HPO methodologies: Syne Tune offers a variety of advanced configurations, such as hyperparameter transfer learning, limited HPO or multi-objective optimization

• Benchmarking: Syne Tune offers a benchmark API and an extensive collection of benchmark implementations. With tabular or surrogate benchmarks and a simulation backend, special emphasis is placed on the possibility of fast and manageable experimentation.

On GitHub, SyneTune is offered as a package. This package offers advanced distributed hyperparameter (HPO) optimizers, which allow trials to be evaluated using a variety of trial backend choices. One can choose between a local backend to evaluate trials locally, SageMaker to evaluate trials as separate SageMaker training jobs, or a simulation backend to quickly evaluate parallel asynchronous schedulers.

The Syne-tune package can be installed using the pip command.

pip install syne-tune

Syne Tune offers the ability to improve the efficiency, reliability and credibility of automated tuning studies. It allows researchers without significant computational resources to participate by elevating the simulation on tabbed benchmarks to first-class status.

This Article is written as a summary article by Marktechpost Staff based on the paper 'Syne Tune: A library for large-scale hyperparameter tuning and reproducible research'. All Credit For This Research Goes To Researchers on This Project. Checkout the paper, github.

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New generation Toyota Innova launched around Diwali https://e-jemed.org/new-generation-toyota-innova-launched-around-diwali/ Sun, 19 Jun 2022 05:30:12 +0000 https://e-jemed.org/new-generation-toyota-innova-launched-around-diwali/ Rendering The new generation of Toyota Innova would go on sale in India later this year and it will be offered with a hybrid gasoline engine Toyota Kirloskar Motor (TKM) is working on a number of new launches for the Indian market. The mid-size SUV known as the Urban Cruiser Hyryder will debut on July […]]]>

Rendering


The new generation of Toyota Innova would go on sale in India later this year and it will be offered with a hybrid gasoline engine

Toyota Kirloskar Motor (TKM) is working on a number of new launches for the Indian market. The mid-size SUV known as the Urban Cruiser Hyryder will debut on July 1, 2022 and will likely be followed by the launch of the fully updated Urban Cruiser compact SUV. Later this calendar year, Toyota also appears to be gearing up to introduce the next-generation Innova.

Around Diwali 2022, the Japanese automaker is expected to bring in the all-new Toyota while the existing model will continue its duties. The third generation Innova would sit on a unibody chassis ditching the ladder frame construction and it will have a more traditional front-wheel-drive setup.

The 2023 Toyota Innova is believed to be based on the TNGA-C platform which can also be found in the global Corolla and it will have some commonality with JDM-spec minivans like Noah. Internally codenamed 560B, it is said to have an overall length of around 4.7 meters and a wheelbase length of 2.85 meters. Although it’s shorter than the Crysta, the longer wheelbase should make for a roomier cabin.

Rendering of the 2023 Toyota Innova Crystal

In addition, the new structure will allow vertically aligned C-pillars and the space between the wheels will be more important. The presence of a unibody construction will make the next Innova lighter by around 170 kg and therefore improved efficiency is very likely. As for performance, a 2.0-liter hybrid gasoline engine will be used with localized THS II technology.

The next-generation Toyota Innova has already been tested and it will likely have an evolutionary approach to design over the existing model and its design will be influenced by the brand’s latest generation of global models, including the Corolla Cross. The interior will be fully modernized with the latest technologies in connectivity, assistance and safety.

toyota innova next generation spied 1

The feature list could offer a larger touchscreen infotainment system with Apple CarPlay and Android Auto wireless connectivity, wireless charging facility, ventilated front seats, reclining captain’s chairs with ottoman function, multiple airbags , automatic climate control and much more.

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The formation and evolution of massive binaries may share the same mechanism in the Milky Way and the Andromeda galaxy https://e-jemed.org/the-formation-and-evolution-of-massive-binaries-may-share-the-same-mechanism-in-the-milky-way-and-the-andromeda-galaxy/ Fri, 17 Jun 2022 05:44:00 +0000 https://e-jemed.org/the-formation-and-evolution-of-massive-binaries-may-share-the-same-mechanism-in-the-milky-way-and-the-andromeda-galaxy/ A research team led by Professor QIAN Shengbang and PhD student LI Fuxing from the Yunnan Observatories of the Chinese Academy of Sciences has found that the formation and evolution of massive binaries in the Milky Way and Andromeda Galaxy ( M31) could share the same mechanism. . Their findings have been published in Monthly […]]]>

A research team led by Professor QIAN Shengbang and PhD student LI Fuxing from the Yunnan Observatories of the Chinese Academy of Sciences has found that the formation and evolution of massive binaries in the Milky Way and Andromeda Galaxy ( M31) could share the same mechanism. .

Their findings have been published in Monthly Notices of the Royal Astronomical Society and The Astrophysical Journal.

The massive binary contains at least one early-type star whose spectral type is O,B type. These binaries have high-energy radiation like X-rays, and they possibly create neutron stars or black holes. The ancestors of these semi-detached binaries are the detached binaries where the more massive original components evolve faster and first fill their critical Roche lobes and then transfer mass to their companions with the evolution of case A.

During this process, the orbital period of the system will be reduced and the mass ratio will be increased. When the system evolves to the critical state where the mass ratio is one (twin binaries), that binary has the shortest orbital period. Then the mass ratio of the binary will reverse with mass transfer from the least massive component to the most massive after this special.

According to the study published in Monthly Notices of the Royal Astronomical Society, the researcher investigated the evolutionary stage of V375 Cassiopeia (V375 Cas), a massive binary and contains two B-type components.

They analyzed the light curves of the V375 Cas and found that the V375 Cas must undergo late mass transfer from the A case from the less massive to the more massive component.

Meanwhile, according to statistics, these massive semi-detached binaries have a third body with different periods. From the HR diagram, the components of the massive binaries are nearly the main sequence stars, and the evolutionary age of the secondary component is greater than that of the primary for V375 Cas. “V375 Cas is a hierarchical triple system where a massive main-sequence star accompanies a massive semi-detached mass transfer binary based on third-light estimation, LI said.

The researchers also discovered two massive close binaries with twin components in M31. M31 is the closest spiral galaxy to the Milky Way and the largest galaxy in the Local Group, and its structure and metallicity are very close to those of the Milky Way.

The photometric solutions are carried out with the WD method from 437 eclipsing binaries, and two twin binaries have been found. One system is a contact binary with a mass ratio of 0.974, and the other system is a semi-detached binary with a mass ratio of 0.924. This result suggests that massive twin binaries are rare in M31.

Based on the study of the changes in orbital period by the OC diagrams and the configurations of the binaries, the researchers found that these two massive twin binaries are at different evolutionary stages with similar mass ratios (close to unity ). The double-contact binary is about to enter the critical shortest period evolutionary phase with rapid mass transfer. The semi-detached binary has gone through this stage of evolution and fails to form a contact binary during the orbit-decreasing phase with the mass transfer of case A.

These findings were published in The Astrophysical Journal.

These two works indicate that the evolution of massive binaries is equally possible in the Milky Way and M31, and these binaries at a particular stage create an ideal test bed of evolutionary models of massive binaries.

/Public release. This material from the original organization/authors may be ad hoc in nature, edited for clarity, style and length. The views and opinions expressed are those of the author or authors. See in full here.

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Global AI-Based Clinical Trial Solution Provider Market 2022 – Industry Analysis, Segments, Value Chain and Key Trends 2028 – Instant Interview https://e-jemed.org/global-ai-based-clinical-trial-solution-provider-market-2022-industry-analysis-segments-value-chain-and-key-trends-2028-instant-interview/ Wed, 15 Jun 2022 04:30:00 +0000 https://e-jemed.org/global-ai-based-clinical-trial-solution-provider-market-2022-industry-analysis-segments-value-chain-and-key-trends-2028-instant-interview/ Global AI-Based Clinical Trial Solution Provider Market is a new publication by MarketsandResearch.biz which details current, historical and evolving patterns in the AI-enabled clinical trial solution provider industry. The report examines the market, which is divided into five major regions. The research also examines the influence of COVID on the market for AI-based clinical trial […]]]>

Global AI-Based Clinical Trial Solution Provider Market is a new publication by MarketsandResearch.biz which details current, historical and evolving patterns in the AI-enabled clinical trial solution provider industry. The report examines the market, which is divided into five major regions. The research also examines the influence of COVID on the market for AI-based clinical trial solution providers at regional and global level. It includes a section dedicated to the major players in the sector. The study covers the history of the industry and its growth prospects over the next few years and reviews the key successful marketers in this market.

Furthermore, the study establishes the market in the context of the geographic distribution of the market. The study offers an insight into the hurdles and restrictions faced by potential entrants in the industry and the threat of alternatives and risks.

The report presents the latest competitive insights and valuable recommendations for businesses and other clients to help them break into the global market or any regional market. Businesses would gain a strategic advantage over their competitors through this report. It also assesses the current situation and outlook of the industry by leveraging the horizon of the project.

DOWNLOAD FREE SAMPLE REPORT: https://www.marketandresearch.biz/sample-request/207060

Type considered in the report:

  • Phase I
  • Stage II
  • Phase-III

Application considered in the report:

  • Pharmaceutical companies
  • Academia
  • Others

The major players represented in the report are:

  • Unlearn.AI, Inc.
  • Saama Technologies
  • Antidote Technologies, Inc.
  • Phesi
  • Deep AI 6
  • Innoplex
  • Mendel.ai
  • Intelligence
  • Middle technologies
  • AI Symphony
  • BioAge Labs, Inc.
  • AiCure, LLC
  • CONSILX
  • IA DEEP LENS
  • Halo Health Systems
  • pharmaceutical seal
  • Ardigen
  • Tests.Ai
  • Koneksa Health
  • Euretos
  • BioSymmetry
  • Google – In truth
  • GNS Health
  • IBM Watson
  • exscientia

Geographically broken down into several main regions:

  • North America (United States, Canada and Mexico)
  • Europe (Germany, France, UK, Russia, Italy and Rest of Europe)
  • Asia-Pacific (China, Japan, Korea, India, Southeast Asia and Australia)
  • South America (Brazil, Argentina, Colombia and rest of South America)
  • Middle East and Africa (Saudi Arabia, United Arab Emirates, Egypt, South Africa and Rest of Middle East and Africa)

ACCESS FULL REPORT: https://www.marketandresearch.biz/report/207060/global-ai-based-clinical-trials-solution-provider-market-growth-status-and-outlook-2021-2026

The report introduces the key features which give an idea about the business models and business segmentations are examined, product portfolios, market share, sales estimates, specializations, growth rates, pricing strategies, l SWOT analysis and other methods are used to analyze data, as well as graphing and analysis

Report customization:

This report can be customized to meet customer requirements. Please contact our sales team (sales@marketsandresearch.biz), who will ensure that you get a report tailored to your needs. You can also get in touch with our executives at +1-201-465-4211 to share your research needs.

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Sony Electronics launches two new premium music players, including the new Signature Series Walkman® with gold-plated oxygen-free copper (OFC) chassis https://e-jemed.org/sony-electronics-launches-two-new-premium-music-players-including-the-new-signature-series-walkman-with-gold-plated-oxygen-free-copper-ofc-chassis/ Mon, 13 Jun 2022 15:00:00 +0000 https://e-jemed.org/sony-electronics-launches-two-new-premium-music-players-including-the-new-signature-series-walkman-with-gold-plated-oxygen-free-copper-ofc-chassis/ Sony Electronics launches two new high-end music players Tweet that The NW-WM1AM2 allows music lovers to completely lose themselves in high-quality sound with a richer, smoother and more expansive sound field than its predecessor. Both music players allow the user to download and stream from countless music catalogs with Wi-Fi compatibility, taking the listening pleasure […]]]>

The NW-WM1AM2 allows music lovers to completely lose themselves in high-quality sound with a richer, smoother and more expansive sound field than its predecessor.

Both music players allow the user to download and stream from countless music catalogs with Wi-Fi compatibility, taking the listening pleasure to the next level.

Great sound starts with great components
Throughout the history of Sony’s high-end music players, audio mastery has been achieved through a combination of meticulous assembly of exceptional components. The NW-WM1ZM2 and NW-WM1AM2 are the products of this philosophy.

Purer materials for purer sound
The NW-WM1ZM2 has a 99.99% pure gold (4N) plated oxygen-free copper (OFC) chassis. This achieves a stronger digital foundation and greater rigidity, allowing for clear and expansive sound, so the listener can experience each instrument as if it were performing live.

The NW-WM1AM2 uses an aluminum alloy frame that provides a highly rigid enclosure that resists electrical noise and other interference creating stable, high quality sound.

Enjoy authentic sound reproduction
Using S-Master™ HX digital amplification technology, independently developed for Walkman®, the NW-WM1ZM2 and NW-WM1AM2 provide surprisingly faithful sound reproduction. The all-digital amplifier further creates rich, full-bodied sound, using high-quality lead-free solder.

Take inspiration from the avant-garde DMP-Z1both music players feature even more powerful power than their previous models, both in the analog and digital block.

The NW-WM1ZM2 and NW-WM1AM2 have upgraded refined capacitors – various FT CAP3 capacitors (high polymer capacitor) and a large solid high polymer capacitor which offers large capacitance and low resistance. A machined OFC block covering the digital block allows both music players to deliver sound that seems to come out of the silence.

Perfect signal integrity
To achieve powerful and smooth sound quality, Sony has selected a thick KIMBER KABLE® to go from the base of the amp to the balanced headphone socket of the NW-WM1ZM2just like the famous DMP-Z1. This carefully selected component allows high-quality audio signals to be transmitted, leaving only the music behind.

The NW-WM1AM2 uses a low resistance OFC cable which provides low distortion and better channel separation.

To achieve the evolving sound of both music players, a dual clock and fine sound register have been precisely placed in each Walkman. For the first time, Sony began to use reflow solder containing gold, the effect of which is significant in improving overall sound localization and expanding sound space.

Get the most out of music, whatever the source
The NW-WM1ZM2 and NW-WM1AM2 both incorporate a DSD remastering engine where PCM (Pulse Code Modulation) audio is resampled into an 11.2 MHz DSD (Direct Stream Digital), providing even more ways to enjoy music.

With the NW-WM1ZM2 and NW-WM1AM2 listeners can also bring their music to life by upscaling compressed music files in real time with DSEE Ultimate™. This evolving algorithm now offers even more benefits for lossless CD-quality audio (16-bit 44.1/48kHz). By restoring acoustic subtleties and dynamic range, the user experiences a richer and fuller listening experience.

Hear every note the way the artist intended
Both players are also compatible with Balanced Connection and High-Resolution Audio, allowing listeners to experience their favorite tunes, just as the artist intended.

moving music
The NW-WM1ZM2 and NW-WM1AM2 are Wi-Fi enabled and powered by Android™ 11, providing access to a huge collection of genres and artists from around the world. Consumers can choose to listen from their favorite music streaming and download services or connect to a PC to download tracks and playlists from personal collections, ensuring high-quality sound playback.

All new optimized usability
With a larger 5.0 inch (12.7 cm) screen, both music players feature a new fluid and responsive touchscreen that has been upgraded to HD (High Definition), optimizing the user experience . Consumers can also customize their home display on the Walkman home screen to suit individual needs, making each Walkman truly unique.

To ensure that listeners can immerse themselves in music wherever they are, both top models offer up to 40 hours[1] non-stop FLAC 96kHz high-resolution audio playback.

One USB Type-C® port features on both models, providing fast transfer of music files and easy connectivity with a range of devices[2].

The NW-WM1ZM2 offers 256GB of built-in memory and a microSD card slot, while the NW-WM1AM2 offers 128GB of built-in memory and a microSD card slot, allowing listeners to take even the largest music collections with them wherever they go.[3]

Sustainability matters
Sony products are not only designed to be stylish, but also to be environmentally friendly. Zero plastic[4] is used in packaging material for the NW-WM1ZM2 and NW-WM1AM2reflecting Sony’s commitment to reducing the impact of our products and practices.

Price and availability:

NW-WM1ZM2 has a suggested retail price of $3,699.99 and is available now for purchase from Sony Electronics and other authorized retailers. For a full list of specifications and information, please visit https://electronics.sony.com/audio/walkman-digital-recorders/walkman-mp3-players/p/nwwm1zm2.

NW-WM1AM2 has a suggested retail price of $1,399.99 and is available now for purchase from Sony Electronics and other authorized retailers. For a full list of specifications and information, please visit https://electronics.sony.com/audio/walkman-digital-recorders/walkman-mp3-players/p/nwwm1am2.

About Sony Electronics Inc.
Sony Electronics is a subsidiary of Sony Corporation of America and a subsidiary of Sony Group Corporation, one of the world’s most comprehensive entertainment companies, with a portfolio that spans electronics, music, film, mobile, games, robotics and financial services. Based at San Diego, California, Sony Electronics is a leader in electronics for the consumer and professional markets. Activities include research and development, engineering, sales, marketing, distribution and customer service. Sony Electronics creates products that innovate and inspire generations, such as award-winning Alpha interchangeable lens cameras and groundbreaking Hi-Res Audio products. Sony is also a leading manufacturer of end-to-end solutions for 4K professional broadcast and A/V equipment to industry leaders 4K and 8K Ultra HD TVs. Visit http://www.sony.com/news for more information.

[1] When using Sony original music player app. Actual performance will vary based on settings, environmental conditions and usage.

[2] USB Type-C cable sold separately

[3] 1 GB equals 1 billion bytes, a portion of which is used for data management functions.

[4] Coating materials and adhesives excluded. This varies by region.

SOURCESony Electronics, Inc.

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The last APR-1400 reactor is now online at the Shin Hanul nuclear power plant in South Korea https://e-jemed.org/the-last-apr-1400-reactor-is-now-online-at-the-shin-hanul-nuclear-power-plant-in-south-korea/ Sat, 11 Jun 2022 20:30:08 +0000 https://e-jemed.org/the-last-apr-1400-reactor-is-now-online-at-the-shin-hanul-nuclear-power-plant-in-south-korea/ The first of what could be up to four APR-1400 nuclear reactors at the Shin Hanul site in South Korea is now supplying electricity to the country’s power grid. Shin Hanul Unit 1 is a 1,400 MW reactor. It was connected to the grid on June 9, just over two weeks after the pressurized water […]]]>

The first of what could be up to four APR-1400 nuclear reactors at the Shin Hanul site in South Korea is now supplying electricity to the country’s power grid.

Shin Hanul Unit 1 is a 1,400 MW reactor. It was connected to the grid on June 9, just over two weeks after the pressurized water reactor reached its first criticality on May 22, according to officials from Korea Hydro & Nuclear Power (KHNP).

South Korean officials said Shin Hanul, located in Uljin on the country’s east coast, was part of the new government’s strategy to ensure energy security while supporting environmental goals. The reactor start-up comes three months after Yoon Suk-yeol was elected as South Korea’s new president. Suk-yeol said he plans to reverse former President Moon Jae-in’s strategy of phasing out nuclear power generation. Jae-in adopted the policy after taking office in 2017, citing in part the 2011 Fukushima Daiichi accident in Japan.

Suk-yeol, however, said nuclear power must remain part of South Korea’s energy mix, and said his administration was considering restarting construction of two more APR-1400s at Shin Hanul. Suk-yeol has said he wants to continue operating the country’s current nuclear reactors for a longer period, and his administration has said nuclear should continue to supply about 30% of South Korea’s electricity.

Design first used in Shin Kori

The first two APR-1400 reactors, Shin Kori Units 3 and 4 in South Korea, entered commercial operation in December 2016 and September 2019, respectively. Construction of two more APR-1400s, designated as Shin Kori Units 5 and 6, began in April 2017 and September 2018, with those reactors scheduled to enter service in March 2023 and June 2024, respectively.

Sama Bilbao y León, director general of the World Nuclear Association, in comments shared with POWERFUL on June 10, said, “Shin Hanul 1 will make a significant contribution to reducing South Korea’s use of fossil fuels by providing affordable, safe and low-carbon electricity. I would like to extend my congratulations to Korea Hydro & Nuclear Power (KHNP), the Korea Nuclear Safety and Security Committee (NSSC) and all those who have contributed to the commissioning of this reactor.

Bringing Shin Hanul 1 online ends a nine-year construction process for the reactor. Groundbreaking for the first two units of Shin Hanul, formerly known as Shin Uljin, began in May 2012. Construction of Units 1 and 2 advanced, with the reactors initially expected to be commissioned in April 2017 and April 2018, respectively, before running into roadblocks, including Jae-in’s phase-out policy that threatened ongoing nuclear projects. Construction of Units 3 and 4 at Shin Hanul has also been suspended.

Amid construction delays, fuel loading for Unit 1 has been pushed back to June 2019. This work was initially postponed after regulators requested more safety checks and modifications. The Nuclear Safety and Security Committee (NSSC) gave conditional approval for Unit 1 start-up on July 9, 2021, and KHNP began loading the first of the fuel assemblies into the reactor core on July 14 from Last year. KHNP in October 2021 said that after loading fuel, it performs reactor physics and systems tests under normal operating temperature and pressure conditions. KHNP previously said it would take around eight months to complete these tests, in line with the eventual start date.

60 year design life

The APR-1400 is a scalable pressurized water reactor, based on the Combustion Engineering, or CE, System 80+ model. The reactor is mainly designed by Korea Engineering Company, with a production capacity of 1,400 Mwe and a lifetime of 60 years.

Officials said the APR-1400 supplants the standardized 995 MWe OPR-1000, a Generation II reactor developed by KHNP and Korea Electric Power Corp. (KEPCO). Nuclear officials and engineers in South Korea said the APR-1400 had improvements in operation, safety, maintenance and accessibility. KHNP, when announcing the grid connection, said Shin Hanul 1 is the country’s first nuclear reactor to achieve “technology independence”, mainly due to the location of central facilities, such as the reactor coolant pump and the plant instrumentation and control system.

The APR-1400 reactor design was approved by European Utility Requirements – a technical advisory group for European utilities on nuclear power plants – in October 2017. The United States Nuclear Regulatory Commission certified in August 2019 that the APR -1400 meets US nuclear security requirements.

The Barakah nuclear power plant, the first nuclear generation in the United Arab Emirates and a POWERFUL Winner of the Top Plant award in 2021, owns four APR-1400s. Barakah represents the first export of the APR-1400 design. Barakah’s first two units have been connected to the grid over the past two years.

KHNP said in April this year that it was in talks with Poland on exporting the technology for building up to six APR-1400 reactors in that country.

“In the face of astronomical fossil fuel prices and the urgent need to tackle climate change, governments around the world must rapidly accelerate the deployment of new nuclear capabilities,” said Bilbao y León. “While South Korea’s brief flirtation with phasing out nuclear power has certainly set back progress, the new administration’s commitment to supporting its nuclear power industry, both in South Korea and in the markets growing export market, is very welcome.”

Darrell Supervisor is associate editor of POWER (@POWERmagazine).

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Powering Payments with AI | Tech Radar https://e-jemed.org/powering-payments-with-ai-tech-radar/ Tue, 07 Jun 2022 14:07:17 +0000 https://e-jemed.org/powering-payments-with-ai-tech-radar/ Cloud (opens in a new tab) IT has led to an explosion of technological possibilities, making it easier than ever to build, test, and scale services in more flexible ways. Its agile nature has enabled companies to deliver existing services while experimenting with powerful technologies without disruption. One of the most exciting examples of this […]]]>

Cloud (opens in a new tab) IT has led to an explosion of technological possibilities, making it easier than ever to build, test, and scale services in more flexible ways. Its agile nature has enabled companies to deliver existing services while experimenting with powerful technologies without disruption.

One of the most exciting examples of this is its activation of artificial intelligence (opens in a new tab) (IA). The availability and affordability of unlimited computing resources in the cloud compared to on-premises resources has spurred the development of AI applications (opens in a new tab) in all industries. According to IDC, spending on UA ​​is expected to increase by 18.8% in 2022 and reach $500 billion by 2024. Enterprises are expected to take advantage of the scale, speed, and affordability of data. (opens in a new tab) processing offered by the cloud, making the adoption of AI a compelling opportunity for businesses.

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Release date, price and specs https://e-jemed.org/release-date-price-and-specs/ Sun, 05 Jun 2022 20:04:18 +0000 https://e-jemed.org/release-date-price-and-specs/ The Subaru Impreza is due for a major refresh, and we’ll probably see it this year. Subaru typically updates its cars on a strict five-year schedule. However, the 2022 Impreza remained unchanged from the previous year. This hints that we can expect a complete redesign of the 2023 Subaru Impreza for this year, although we’re […]]]>

The Subaru Impreza is due for a major refresh, and we’ll probably see it this year. Subaru typically updates its cars on a strict five-year schedule. However, the 2022 Impreza remained unchanged from the previous year. This hints that we can expect a complete redesign of the 2023 Subaru Impreza for this year, although we’re still awaiting a few key details.

When is the 2023 Subaru Impreza coming out?

The Subaru Impreza is due for a redesign | Robert Hradil/Getty Images

Subaru didn’t provide an official release date for the 2023 Impreza, but we imagine it will closely align with that of the 2023 Subaru Legacy. We’ll likely see both of these all-wheel-drive cars in the fall.

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The best chair for the job might not be what you think https://e-jemed.org/the-best-chair-for-the-job-might-not-be-what-you-think/ Sat, 04 Jun 2022 04:00:45 +0000 https://e-jemed.org/the-best-chair-for-the-job-might-not-be-what-you-think/ For several centuries, the design of office chairs has been oriented towards a single ideal: a chair so comfortable that workers could spend eight hours without having to move. Thomas Jefferson was an early pioneer of this “do less to do more” philosophy when, in 1776, the future president inserted a rod and casters under […]]]>

For several centuries, the design of office chairs has been oriented towards a single ideal: a chair so comfortable that workers could spend eight hours without having to move. Thomas Jefferson was an early pioneer of this “do less to do more” philosophy when, in 1776, the future president inserted a rod and casters under his Windsor chair to create the world’s first swivel chair. In 1840, Charles Darwin fitted wheels to his chair and used it to slide between specimen drawers.

Today’s ergonomic office chairs are equipped with half a dozen buttons that help you position your body in the ideal way. They are designed to reduce the stresses of this long-term immobility, otherwise known as “office life”. The webbed material used in Herman Miller’s iconic Aeron chair, for example, was originally developed to prevent pressure sores. Such innovations are ergonomic marvels, if we mean by ergonomics “something that helps you work more”.

But, for proponents of “active sitting, every improved lumbar support and padded armrest is one step away from light. Talking to an active chair evangelist for the first time is something like discovering that you have the function of an everyday object entirely upside down. Are you comfortably seated? Too bad, but I’ll start.

The first thing I must warn you about the active chair community is that its prescriptions have yet to be proven. Active chairs have been around since 1979, when Norwegian designer Hans Christian Mengshoel patented a kneeling chair with a rocking mechanism called Balans. He sparked decades of innovation, most notably from fellow countryman Peter Opsvik, whose unusual designs included a desk chair suspended from the ceiling. Opsvik’s son, Tor, remembers a childhood home where you had to have a death wish to change a light bulb, because everything shook wildly when you stood on it.

Although Opsvik and his contemporaries remain respected as designers, much of the “evidence” for active sitting is extrapolated from evolutionary biology (cavemen didn’t need lumbar support, so why should we?!) And studies in areas of the world where people don’t suffer from back pain. These are usually places where less time is spent in the 90°-90°-90° posture promoted by a traditional chair, where the knees, hips and elbows are all positioned at 90°. Japan in the first half of the 20th century, with its coffee tables, is an example.

Ergonomic design guru Peter Opsvik on his Globe Garden chair – a tiny piece at £4,287.98 from Archiproducts

Although there is strong evidence that prolonged sitting has negative health effects, there is no conclusive evidence that these consequences are mitigated by sitting in a chair that requires you to make micro-adjustments. to your posture. A 2010 literature review of Balans chairs, commissioned by American furniture manufacturer Varier, concluded that “for some users. . . the ability to alternate between these postures can provide significant benefits” – a particularly tentative summary given that Varier manufactures the chairs in question.

The second thing I must warn you is that, reader, I am a believer. Five months ago I bought a counterfeit Balans chair which has profoundly improved my working life. Before he arrived, I used to sit on the couch when I worked from home. Not out of laziness, but because I am chronically restless and it was the only place that allowed me to constantly position and reposition myself. I stared at my pristine desk and dreamed of what it would be like to work without my laptop warming my lap.


As I write this, however, I’m sitting (well, kneeling) at that same desk – upright, engaged, and gently swaying to make sure I stay that way. After a decade of discomfort, it feels like a revelation, like unlocking the power of a “walk and talk” without leaving the room. Because the chair requires me to engage my heart, I can’t use it all day without breaks, but that’s okay. I currently have the luxury of setting my own hours, so why emulate the presenteeism of lunch at the office from nine to five?

The biggest downside to my kneeling chair is that it’s honestly very ugly. Although a good salesman touts his Scandinavian origins, as if that alone imparts impeccable taste, the truth is that the U-shaped plywood stool resembles a rocking horse crossed with something found in a rehabilitation room. One of my partner’s only opinions of our interior design is that the “weird chair” lives deep under the desk when not in use.

My first thought on entering Back in Action, an active chair specialist with a showroom in London, is that my partner should count himself lucky. My weird chair looks harmless among the game toys for sale here. A chair is shaped like a mushroom and boings like a pogo stick the moment you make contact. Some stools have convex bases that allow them to spin around like tops. As I perch awkwardly on a £729 seat with old-fashioned leg rockers, business consultant Craig Brown pulls out a model of the human spine and tries to explain what these very distinctive seats are all about common.

First, they put you in a posture where the pelvis is raised above the knees. “If you can’t get your hips higher than your knees, what happens is the pelvis moves back. You get a C-shape in your spine,” says Brown, contorting the skeleton into an unfortunate collapse.

The lumbar support provided by an ergonomic office chair will push the spine back into its “correct” shape, but because the pelvis remains tilted, the spine is still under tension.

The second thing an active chair should do is allow you to move. This is where the Balans lose points. On a video call from Vermont, surgeon-turned-inventor Turner Osler frowns in concern when I proudly tell him what I’m sitting on. “The kneeling chair locks you into one position,” he says. “It’s hard to squirm.”

Osler, who founded his company QOR360 (pronounced “core 360”) in 2016, sits on the Ariel as he talks to me. It looks a bit like a bar stool, only the seat is able to swivel in all directions. His living room is filled with prototypes, including a DIY version of the Ariel that uses a tennis ball as a pivot and which he hopes will take off in schools. “The chair industry has worked really hard to make comfortable chairs so people don’t feel like they have to move, and that’s a disaster,” he says. Osler is passionate, even polemical. He introduces me to the concept of “Big Chair” – a cabal to rival Big Oil or Big Pharma – and tells a story I dare not print of when an agent of this sleazy lobby group scuttled his chances of get his chair in the hands of a VIP couple. “They want to kill us,” he says of Big Chair. I think he’s kidding.


After our conversation, I send an e-mail Osler and ask him to send me the most compelling scientific evidence for active sitting. “It’s still early,” he writes, even though it’s been over 40 years. Top of its list is a 2019 study that found that sitting in a balance chair burned more calories than sitting in a standard office chair or exercise ball. Hopefully more research on active sitting will come soon and take calorie burning out of the first place, since it’s a particularly miserable reason to do anything. But in his absence, I will offer my own call.

In so many areas of life, we try new things without thinking twice. You might see a subway ad for home shopping or a mattress delivered in a box, and habits you thought were deep-rooted can change almost overnight. But the norms of office life prevent experimentation.

Task chairs are rarely purchased by the people who sit in them. Most companies have aesthetic priorities and safety standards — a five-star wheelbase, for example — that active chairs don’t meet. Practical concerns aside, it’s hard to get over the fact that they look so weird, so medical. Short of being the CEO of a start-up, who among us would want to put our heads upside down while strutting on a mushroom? In the cool office hierarchy, warning coworkers about their C-shaped spines is like bringing your own water filter to work.

Working from home, however, presents new opportunities. It’s no coincidence that Opvsik, Osler and Brown are all reporting very strong sales during the time when most people were stuck at home. “They were in charge of their own workspace,” says Brown in the Marylebone showroom. Your active chair can stay hidden, as well as your slippers.

In a recent essay for The Architectural Review on the gendered history of chair design, historian Catharine Rossi suggests the following thought experiment: “The next time you feel uncomfortable in a chair, ask you if yours is a body it was designed for — and if not, why not?”

So much has been written about how we might work after the pandemic. An evolution towards flexibility and customization is often presented as the only reward for a few terrible years. If you were one of the lucky few for whom that promise held some substance, you might be able to ask yourself some version of Rossi’s question the next time you sit down at your desk. Does your current way of working match what this chair was designed for? And, if not, could there be a better option out there?

If I disappear this week, you will know where to find me; deep in the basement of Big Chair, strapped to a plush executive lounger while I await my rescue. At least I’ll be comfortable.

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Presence of monkeypox virus in distant small mammal species https://e-jemed.org/presence-of-monkeypox-virus-in-distant-small-mammal-species/ Thu, 02 Jun 2022 14:33:00 +0000 https://e-jemed.org/presence-of-monkeypox-virus-in-distant-small-mammal-species/ A recent study published on Research Square* The preprint server showed that tiny mammalian species far removed from the Democratic Republic of Congo (DRC) harbor monkeypox virus (MPXV). Study: Monkeypox viruses circulate in distant small mammal species in the Democratic Republic of the Congo. Image Credit: FOTOGRIN/Shutterstock Background The MPXV, belonging to the Orthopoxvirus (OPXV) […]]]>

A recent study published on Research Square* The preprint server showed that tiny mammalian species far removed from the Democratic Republic of Congo (DRC) harbor monkeypox virus (MPXV).

Study: Monkeypox viruses circulate in distant small mammal species in the Democratic Republic of the Congo. Image Credit: FOTOGRIN/Shutterstock

Background

The MPXV, belonging to the Orthopoxvirus (OPXV) under genus Poxviridae family, causes human monkeypox, a zoonotic disease. Its clinical manifestations are similar to smallpox. The case fatality rate in adults is generally low, but can exceed 10% in children.

Two MPXV genetic clades have been recognized in Africa, where the virus is commonly found. The genetic clades discerned are a Congo Basin clade (MPXV-CB) found exclusively in Central Africa and a West African clade (MPXV-WA) found only in countries west of Cameroon.

Although MPXV-CB was previously thought to be more transmissible and virulent in humans due to small sample size, the 2017-2018 MPXV-WA outbreak in Nigeria revealed the increased virulence of MPXV- WA. The increasing prevalence and interpersonal transmission of both strains in endemic regions highlights the need to better understand the eco-epidemiological determinants of the disease.

The natural reservoir of MPXV is unknown, as is the putative animal source of the initial human infections. MPXV has only been extracted from three native African wild mammals: Funisciurus anerythrus (tree squirrel without red) in the DRC and Cercocebus atys atys (a sooty mangabey), Pan troglodyte verus (western chimpanzees) in the Ta National Park in Côte d’Ivoire.

While primates are considered accidental hosts, rodents such as Heliosciurus sp., Cricetomys, Funisciurus and Graphiurus are considered possible reservoirs of the virus. Nevertheless, empirical evidence supporting these theories is limited and mostly centered on serological information or deoxyribonucleic acid (DNA) amplicons lacking sequencing confirmation.

About the study

In current work, researchers have evaluated complete and near-complete MPXV genomes in a Crocidura littoralis (shrew), Funisciurus bayonii and F. anerythrus (squirrels) of the DRC. Additionally, they assessed Cricetomys sp. 2 and Stochomys longicaudatus (rats) for the presence of MPXV sequences.

The team has been monitoring small mammal biodiversity and pathogens at numerous sites in the Tshopo and Ituri provinces of the DRC since 2010. A subset of 256 randomly selected samples, including tissues taken from six years with 97 rodents, 93 shrews and 66 bats, were tested. for the existence of MPXV DNA using two polymerase chain reaction (PCR) assessments targeting distinct viral genes (haemagglutinin and P4A), with positives validated by Sanger sequencing. Researchers applied high-throughput sequencing and solution hybridization capture to F. anerythrus, C. littoralisand F. bayoni.

Results and discussions

The results of the study demonstrated that the tissues of four rodent species, namely Funisciurus bayonii, Funisciurus anerythrus, Cricetomys sp. 2, and Stochomys longicaudatusand a shrew, Crocidura littoralis, Hosted MPXV DNA. The team succeeded in extracting two whole MPXV genomes from C. littoralis, F. anerythrusand a partial genome (59%) of F. bayoni. Therefore, MPXV probably circulates spontaneously in many distant rodent species from at least three different families, in particular Nesomyidae, Squirrelsand murids, and in shrews of the order Eulipotyphla. Although few of these detection incidences may indicate dead-end infections, they were consistent with the idea that MPXV has a wide host diversity and potentially a complicated multi-host ecology.

The fact that MPXV was originally extracted from a squirrel Funisciurus may have skewed the authors’ view of the ecology of MPXV, as a multitude of follow-up research has focused on squirrels and may have overlooked other orders of squirrels. animals such as bats or shrews. The researchers also pointed out that the definition of a primary reservoir may vary depending on the situation.

In addition, the MPXVs reported in the F. anerythrus and shrew were strongly correlated with each other and belong to the range of MPXV strains observed in people in Central Africa, according to Bayesian and maximum likelihood (ML) phylogenetic studies. They also possessed the time to most recent common ancestor (tMRCA), based on the closest reported genomes to 1959. ML analysis of partial MPXV genome discovered in F. bayoni revealed that it clusters with other strains of MPXV-CB.

The discovery of new sequences of animal origin allowed researchers to reassess the long-standing theory that MPXV diversity was primarily due to past vicariance processes triggered by climate-mediated forest habitat constriction, such as the Opening of the Dahomey Breach or the Last Glacial Maximum. Interestingly, the scientists found such diversity to be very recent to be consistent with these occurrences, with the best model placing the root of the MPXV tree at around 600 years old.

Nevertheless, given the minor variance between MPXV-CB and MPXV-WA, the team did not anticipate that this could have a significant impact on the projected evolutionary timescale of MPXV, making it compatible with the parameters important climatic conditions as presented by Nakazawa et al. Instead, they speculate that the geographic separation of the two clades occurred more recently or that alternative evolutionary factors were at work.

conclusion

Overall, the present research implies that in addition to squirrels (families Nesomyidae and murids) and shrews (order Eulipotyphla), several other rodents could be possible virus reservoirs for monkeypox. Furthermore, the results add to the scant evidence that Funisciurus squirrels could be key reservoirs for the MPXV.

In conclusion, the present study improves the understanding of MPXV ecology by demonstrating the prevalence of MPXV DNA in many forest-dwelling rodents and shrews. This finding requires increased surveillance in a wider range of African mammals to learn more about the distribution and host range of MPXV and to analyze whether various cohorts of animals possess different strains of MPXV with varying virulence.

*Important Notice

Research Square publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be considered conclusive, guide clinical practice/health-related behaviors, or treated as established information.

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